Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.

Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.

To investigate the relationship between a set of six candidate genes and the risk of diabetic retinopathy (DR) in a cohort of Chinese patients town community with type 2 diabetes mellitus (T2DM).


METHOD
A population-based cross-sectional study. Diabetic subjects were recruited from the urban community in Beijing and categorized into groups of proliferative diabetic retinopathy (PDR), non-proliferative diabetic retinopathy (NPDR), or diabetes without retinopathy (DWR) by fundus photography and duration of diabetes.

Six candidate genes, including glycation end certain products receptor sophisticated (AGER), aldose reductase (AKR1B1), inducible nitric oxide synthase (iNOS), pigment epithelium derived factor (PEDF), tumor necrosis factor-alpha (TNF-α), and paraoxonase 1 (PON1), selected by Meta-analysis of genetic association study for DR and biochemical pathways involved in the development of DR. Allele and genotype distribution of 21 functional single nucleotide polymorphisms (SNPs) in their six candidate genes were investigated using the genotype MassARRAY system.


RESULTS
Among the 1461 patients with diabetes were recruited from the community, 569 have been selected in the following genotypic analysis, including 97 patients with PDR, with NPDR 217, and 255 with DWR. For promoter variant rs1051993 in AGER gene, allele and genotype distribution in PDR group differ from those in the group DWR (allele: P = 0.011; genotype: P = 0.01).

Compared with DWR, patients with PDR had a lower frequency of heterozygous genotype GT (9.8% for DWR, 1% for PDR, OR: 0.10, 95% CI: 0.01 to 0.72) and minor alleles T (4.9% for DWR, 0.5% for PDR, OR: 0.10, 95% CI: 0.01 to 0.75). In the multivariate model, the distribution of genotypes of rs1051993 in PDR group were significantly different from those in the group DWR (GT vs GG: OR: 0.07, 95% CI: 0.01 to 0.61, P <0.001). No association with DR SNP observed in other genotypes.


CONCLUSION
The data showed a significant association of rs1051993 variant in the gene promoter AGER with PDR in the Chinese group with type 2 diabetes.

 Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.
Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.

Sector retinitis pigmentosa: Report of ten cases and review of the literature.

To describe the genotypic and phenotypic ten patients with retinitis pigmentosa sector (RP). We also review previously reported mutations associated with RP sector and provide discussions about possible underlying pathophysiological mechanisms.

Patients underwent detailed ophthalmological examination, fundus photography, fundus autofluorescence (FAF) imaging, spectral-domain optical coherence tomography (SD-OCT), as well as visual field and electroretinographic testing. All patients underwent a genetic test to identify the molecular etiology of their disease.


result
A total of ten patients studied. Among these patients, nine had mutations in RHO (c.677T> C; p.Leu226Pro (Novel), c.68C> A; p.Pro23His, c.808A> C; p.Ser270Arg, c.44A> G; p .Asn15Ser, and c.325G> A; p.Gly109Arg), and one patient had a mutation in RPGR (c.3092_3093delAG; p.Glu1031Glyfs * 47). All patients with missense mutations in RHO have visual acuities (VAS) better than 20/30 and showed sustained ellipsoid zone retinal foveal and topped structure.

Patients with deletion c.3092_3093delAG in RPGR have a VA of 20/60 oculus dexter (OD) and the 20/400 oculus sinister (OS), as well as significant foveal contour thinning and atrophy. All patients showed changes in pigment, or marked atrophy along the lower arcade, or both. This pattern of degeneration associated with visual disabilities and hyperFAF and superior hypo.

p73 antibody

70R-34351 100 ug
EUR 327.00
Description: Rabbit polyclonal p73 antibody

p73 antibody

70R-37515 100 ug
EUR 273.00
Description: Rabbit Polyclonal p73 antibody

p73 antibody

70R-50511 100 ul
EUR 287.00
Description: Purified Polyclonal p73 antibody

p73 antibody

70R-50512 100 ul
EUR 244.00
Description: Purified Polyclonal p73 antibody

p73 Antibody

ABF5465 100 ug
EUR 438.00

p73 Antibody

ABF6015 100 ug
EUR 438.00

p73 Antibody

ABF0322 100 ug
EUR 438.00

p73 Antibody

48918-100ul 100ul
EUR 333.00

p73 Antibody

48918-50ul 50ul
EUR 239.00

p73 antibody

20R-1924 50 ug
EUR 281.00
Description: Rabbit polyclonal p73 antibody

p73 antibody

20R-2256 50 ug
EUR 281.00
Description: Rabbit polyclonal p73 antibody

p73 Antibody

33579-100ul 100ul
EUR 252.00

p73 Antibody

33579-50ul 50ul
EUR 187.00

p73 Antibody

20-abx008608
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

p73 Antibody

AF0322 200ul
EUR 304.00
Description: p73 antibody detects endogenous levels of total p73.

p73 Antibody

AF5465 200ul
EUR 304.00
Description: p73 Antibody detects endogenous levels of total p73.

p73 Antibody

AF6015 200ul
EUR 304.00
Description: p73 Antibody detects endogenous levels of total p73.

HA- p73

PVT7187 2 ug
EUR 266.00

P73 Polyclonal Antibody

E-AB-33613-120uL 120uL
EUR 257.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human P73 for WB,IHC-p,ELISA applications.

P73 Polyclonal Antibody

E-AB-33613-20uL 20uL
EUR 130.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human P73 for WB,IHC-p,ELISA applications.

P73 Polyclonal Antibody

E-AB-33613-60uL 60uL
EUR 175.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human P73 for WB,IHC-p,ELISA applications.

P73 Polyclonal Antibody

E-AB-33614-120uL 120uL
EUR 257.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse,Rat P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-33614-20uL 20uL
EUR 130.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse,Rat P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-33614-60uL 60uL
EUR 175.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse,Rat P73 for WB,ELISA applications.

p73 antibody (Tyr99)

70R-34350 100 ug
EUR 327.00
Description: Rabbit polyclonal p73 antibody (Tyr99)

p73 antibody (Tyr99)

70R-37139 100 ug
EUR 349.00
Description: Rabbit Polyclonal p73 antibody (Tyr99)

p73 Polyclonal Antibody

ABP53074-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K321

p73 Polyclonal Antibody

ABP53074-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K321

p73 Polyclonal Antibody

ABP53074-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K321

p73 Polyclonal Antibody

ABP53075-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse, Rat. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K327

p73 Polyclonal Antibody

ABP53075-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse, Rat. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K327

p73 Polyclonal Antibody

ABP53075-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse, Rat. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-acetylation site of K327

p73 Polyclonal Antibody

ABP56441-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from the Internal region of human p73 at AA range: 240-320
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p73 at AA range: 240-320

p73 Polyclonal Antibody

ABP56441-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from the Internal region of human p73 at AA range: 240-320
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p73 at AA range: 240-320

p73 Polyclonal Antibody

ABP56441-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from the Internal region of human p73 at AA range: 240-320
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human. This p73 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p73 at AA range: 240-320

p73 Polyclonal Antibody

ABP52141-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-phosphorylation site of Y99

p73 Polyclonal Antibody

ABP52141-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-phosphorylation site of Y99

p73 Polyclonal Antibody

ABP52141-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from human p73 around the non-phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 from Human, Mouse. This p73 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the non-phosphorylation site of Y99

p73 Conjugated Antibody

C48918 100ul
EUR 397.00

p73 Polyclonal Antibody

41319-100ul 100ul
EUR 252.00

p73 Polyclonal Antibody

41319-50ul 50ul
EUR 187.00

p73 Polyclonal Antibody

41736-100ul 100ul
EUR 252.00

p73 Polyclonal Antibody

41736-50ul 50ul
EUR 187.00

p73 Polyclonal Antibody

41737-100ul 100ul
EUR 252.00

p73 Polyclonal Antibody

41737-50ul 50ul
EUR 187.00

p73 Blocking Peptide

20-abx063387
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

p73 (pT99) Antibody

20-abx009875
  • EUR 314.00
  • EUR 467.00
  • EUR 203.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

p73 (pY99) Antibody

abx011313-100ug 100 ug
EUR 439.00
  • Shipped within 5-10 working days.

P73 Polyclonal Antibody

E-AB-10516-120uL 120uL
EUR 257.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
  • Purified by: Affinity purification
  • Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to s
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-10516-20uL 20uL
EUR 130.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
  • Purified by: Affinity purification
  • Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to s
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-10516-60uL 60uL
EUR 175.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
  • Purified by: Affinity purification
  • Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to s
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-32490-120uL 120uL
EUR 257.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-32490-20uL 20uL
EUR 130.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

P73 Polyclonal Antibody

E-AB-32490-60uL 60uL
EUR 175.00
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivatio
  • Show more
Description: Rabbit antibody against Human,Mouse P73 for WB,ELISA applications.

p73 (pT86) Antibody

abx219067-100ug 100 ug
EUR 439.00
  • Shipped within 5-10 working days.

p73 (pS388) Antibody

abx219068-100ug 100 ug
EUR 439.00
  • Shipped within 5-10 working days.

p73 Blocking Peptide

AF0322-BP 1mg
EUR 195.00

p73 Blocking Peptide

AF5465-BP 1mg
EUR 195.00

p73 Blocking Peptide

AF6015-BP 1mg
EUR 195.00

p73 Polyclonal Antibody

ES3140-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 Polyclonal Antibody

ES3140-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 Polyclonal Antibody

ES4073-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 Polyclonal Antibody

ES4073-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 Polyclonal Antibody

ES4074-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 Polyclonal Antibody

ES4074-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 Polyclonal Antibody

ES7440-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 Polyclonal Antibody

ES7440-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Anti-p73 antibody

STJ96708 200 µl
EUR 197.00
Description: Rabbit polyclonal to p73.

Anti-p73 antibody

STJ96709 200 µl
EUR 197.00
Description: Rabbit polyclonal to p73.

Anti-p73 antibody

STJ94925 200 µl
EUR 197.00
Description: Rabbit polyclonal to p73.

Anti-p73 antibody

STJ94926 200 µl
EUR 197.00
Description: Rabbit polyclonal to p73.

p73 (Phospho- Thr86) Antibody

ABF8296 100 ug
EUR 438.00

p73 (Phospho- Ser388) Antibody

ABF8500 100 ug
EUR 438.00

p73 recombinant monoclonal antibody

A5272 100ul X 3
EUR 595.00
  • Comparisons between Mnoclonal, Polyclonal and Recombinant antibodies and their benefits: Regular monoclonal antibodies have higher purity, better specificity and less lot-to-lot variations than polyclonal antibodies. Recombinant antibodies, however,
  • Show more
Description: A recombinant monoclonal antibody from rabbit against human p73 for WB, IHC,ELISA

Phospho- p73 (Tyr99) Antibody

ABF3015 100 ug
EUR 438.00

p73 (Phospho-Thr86) Antibody

12622-100ul 100ul
EUR 252.00

p73 (Phospho-Thr86) Antibody

12622-50ul 50ul
EUR 187.00

p73 (Phospho-Ser388) Antibody

12772-100ul 100ul
EUR 252.00

p73 (Phospho-Ser388) Antibody

12772-50ul 50ul
EUR 187.00

p73 (Phospho-Tyr99) Antibody

11058-100ul 100ul
EUR 252.00

p73 (Phospho-Tyr99) Antibody

11058-50ul 50ul
EUR 187.00

p73 (Ab-99) Antibody

21075-100ul 100ul
EUR 252.00

p73 (Ab-99) Antibody

21075-50ul 50ul
EUR 187.00

p73 (pY99) Blocking Peptide

20-abx063386
  • EUR 314.00
  • EUR 509.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

Phospho-p73 (Tyr99) Antibody

AF3015 200ul
EUR 304.00
Description: Phospho-p73 (Tyr99) Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.

Phospho-p73 (Thr86) Antibody

AF8296 200ul
EUR 376.00
Description: p73 (Phospho-Thr86) Antibody detects endogenous levels of p73 only when phosphorylated at Thr86.

Phospho-p73 (Ser388) Antibody

AF8500 200ul
EUR 376.00
Description: p73 (Phospho-Ser388) Antibody detects endogenous levels of p73 only when phosphorylated at Ser388.

Anti-p73/TP73 Antibody

PB9235 100ug/vial
EUR 334.00

Anti-P73 alpha Antibody

PA1064 100ug/vial
EUR 334.00

anti-p73 (Ab-99)

LF-PA20377 100 ul
EUR 334.00
Description: Rabbit polyclonal to p73

anti-p73 (Phospho-Tyr99)

LF-PA20378 100 ul
EUR 354.00
Description: Rabbit polyclonal to p73 (Phospho-Tyr99)

Tumor Protein P73 (TP73) Antibody

20-abx212029
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx212030
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

abx332222-100ul 100 ul
EUR 425.00
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx324682
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx325464
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx327414
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx327493
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx323526
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx323607
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

p73 (Acetyl Lys321) Polyclonal Antibody

ABP50113-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys321) from Human. This p73 Acetyl Lys321) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K321

p73 (Acetyl Lys321) Polyclonal Antibody

ABP50113-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys321) from Human. This p73 Acetyl Lys321) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K321

p73 (Acetyl Lys321) Polyclonal Antibody

ABP50113-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K321
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys321) from Human. This p73 Acetyl Lys321) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K321

p73 (Acetyl Lys327) Polyclonal Antibody

ABP50114-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys327) from Human, Mouse, Rat. This p73 Acetyl Lys327) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K327

p73 (Acetyl Lys327) Polyclonal Antibody

ABP50114-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys327) from Human, Mouse, Rat. This p73 Acetyl Lys327) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K327

p73 (Acetyl Lys327) Polyclonal Antibody

ABP50114-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from the human p73 around the acetylation site of K327
  • Applications tips:
Description: A polyclonal antibody for detection of p73 Acetyl Lys327) from Human, Mouse, Rat. This p73 Acetyl Lys327) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human p73 around the acetylation site of K327

p73 (phospho Tyr99) Polyclonal Antibody

ABP50392-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from human p73 around the phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 phospho Tyr99) from Human, Mouse. This p73 phospho Tyr99) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the phosphorylation site of Y99

p73 (phospho Tyr99) Polyclonal Antibody

ABP50392-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from human p73 around the phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 phospho Tyr99) from Human, Mouse. This p73 phospho Tyr99) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the phosphorylation site of Y99

p73 (phospho Tyr99) Polyclonal Antibody

ABP50392-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from human p73 around the phosphorylation site of Y99
  • Applications tips:
Description: A polyclonal antibody for detection of p73 phospho Tyr99) from Human, Mouse. This p73 phospho Tyr99) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p73 around the phosphorylation site of Y99

Tumor Protein P73 (TP73) Antibody

abx034143-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

abx034143-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

abx037215-100ug 100 ug
EUR 391.00
  • Shipped within 5-10 working days.

Tumor Protein P73 (TP73) Antibody

20-abx005990
  • EUR 411.00
  • EUR 592.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Phospho-p73 (Tyr99) Blocking Peptide

AF3015-BP 1mg
EUR 195.00

Phospho-p73 (Thr86) Blocking Peptide

AF8296-BP 1mg
EUR 195.00

Phospho-p73 (Ser388) Blocking Peptide

AF8500-BP 1mg
EUR 195.00

p73 (Ab-99) Conjugated Antibody

C21075 100ul
EUR 397.00

p73 (Acetyl Lys321) Polyclonal Antibody

ES1112-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 (Acetyl Lys321) from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 (Acetyl Lys321) Polyclonal Antibody

ES1112-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 (Acetyl Lys321) from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 (Acetyl Lys327) Polyclonal Antibody

ES1113-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 (Acetyl Lys327) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 (Acetyl Lys327) Polyclonal Antibody

ES1113-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 (Acetyl Lys327) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p73 (phospho Tyr99) Polyclonal Antibody

ES1391-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against p73 (phospho Tyr99) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p73 (phospho Tyr99) Polyclonal Antibody

ES1391-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against p73 (phospho Tyr99) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Anti-p73 Rabbit Monoclonal Antibody

M00688 100ug/vial
EUR 397.00
Description: Rabbit Monoclonal p73 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Antibody for Human p73 (pTyr99)

SPC-1413D 0.1ml
EUR 354.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is unconjugated.

Antibody for Human p73 (pTyr99)

SPC-1413D-A390 0.1ml
EUR 401.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 390.

Antibody for Human p73 (pTyr99)

SPC-1413D-A488 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 488.

Antibody for Human p73 (pTyr99)

SPC-1413D-A565 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 565.

Antibody for Human p73 (pTyr99)

SPC-1413D-A594 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 594.

Antibody for Human p73 (pTyr99)

SPC-1413D-A633 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 633.

Antibody for Human p73 (pTyr99)

SPC-1413D-A655 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 655.

Antibody for Human p73 (pTyr99)

SPC-1413D-A680 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 680.

Antibody for Human p73 (pTyr99)

SPC-1413D-A700 0.1ml
EUR 400.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to ATTO 700.

Antibody for Human p73 (pTyr99)

SPC-1413D-ALP 0.1ml
EUR 394.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Alkaline Phosphatase.

Antibody for Human p73 (pTyr99)

SPC-1413D-APC 0.1ml
EUR 399.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to APC .

Antibody for Human p73 (pTyr99)

SPC-1413D-APCCY7 0.1ml
EUR 471.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to APC/Cy7.

Antibody for Human p73 (pTyr99)

SPC-1413D-BI 0.1ml
EUR 396.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Biotin.

Antibody for Human p73 (pTyr99)

SPC-1413D-DY350 0.1ml
EUR 414.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Dylight 350.

Antibody for Human p73 (pTyr99)

SPC-1413D-DY405 0.1ml
EUR 403.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Dylight 405.

Antibody for Human p73 (pTyr99)

SPC-1413D-DY488 0.1ml
EUR 393.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Dylight 488.

Antibody for Human p73 (pTyr99)

SPC-1413D-DY594 0.1ml
EUR 395.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Dylight 594.

Antibody for Human p73 (pTyr99)

SPC-1413D-DY633 0.1ml
EUR 390.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to Dylight 633.

Antibody for Human p73 (pTyr99)

SPC-1413D-FITC 0.1ml
EUR 392.00
Description: A polyclonal antibody for p73 (pTyr99) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human p73 around the phosphorylation site of tyrosine 99 (pTyr99).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000). This p73 (pTyr99) antibody is conjugated to FITC.

conclusion
Sector RP is a rare form of RP in which only one or two quadrants of the retina display signs of clinical pathology. Most cases are caused by mutations in RHO. These data confirmed earlier reports phenotypic manifestations of RP sector. Low retinal quadrants may be more severely affected because of greater exposure to light.

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