Qvd Apexbio

SC 57461A

A4408-5 5 mg
EUR 171
Description: SC-57461A is a selective inhibitor of human recombinant LTB4 with IC50 value of 49 nM [1].LTB4 (leukotriene B (4)) is a leukotriene and plays an important role in inflammation.

Apexbio Reagents Laboratories manufactures the qvd apexbio reagents distributed by Genprice. The Qvd Apexbio reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Apexbio Reagents. Other Qvd products are available in stock. Specificity: Qvd Category: Apexbio

PD 150606

5 mg
EUR 144
Description: PD 150606 is a specific inhibitor of calpain with Ki value of 0.21 ?M and 0.37 ?M for mu- and m- calpains, respectively [1].

PMPA (NAALADase inhibitor)

10 mg
EUR 206
Description: PMPA is a selective inhibitor of NAALADase with Ki value of 275 pM [1].NAALADase also known as GCPII is a zinc metalloenzyme that resides in membranes and involves in the catalyzing process of neuropeptide NAAG to NAA and glutamate.

PMPA (NAALADase inhibitor)

25 mg
EUR 398
Description: PMPA is a selective inhibitor of NAALADase with Ki value of 275 pM [1].NAALADase also known as GCPII is a zinc metalloenzyme that resides in membranes and involves in the catalyzing process of neuropeptide NAAG to NAA and glutamate.

PMPA (NAALADase inhibitor)

5 mg
EUR 163
Description: PMPA is a selective inhibitor of NAALADase with Ki value of 275 pM [1].NAALADase also known as GCPII is a zinc metalloenzyme that resides in membranes and involves in the catalyzing process of neuropeptide NAAG to NAA and glutamate.

ZJ 43

10 mg
EUR 519
Description: IC50: 2.4 nMZJ-43 is a N-acetylaspartylglutamate (NAAG) peptidase inhibitor. The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) is reported to act as an agonist at group II metabotropic glutamate receptors.

AZ 10417808

5 mg
EUR 383
Description: AZ 10417808 is a selective caspase-3 inhibitor with IC50 value of 14.9 uM [1].The caspase-3 protein is a member of the cysteine-aspartic acid protease (caspase) family.

Ivachtin

1 mg
EUR 113
Description: Ivachtin is a potent inhibitor of caspase-3 with IC50 value of 23 nM [1]. Caspase-3 is a member of the cysteine-aspartic acid protease family and interacts with caspase-8 and caspase-9. Sequential activation of caspases plays an important role in cell apoptosis.

Human Samples information

Ac-IEPD-AFC

A4418-5 5 mg
EUR 324
Description: Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.

Ac-LEHD-AFC

A4419-10 10 mg
EUR 355
Description: Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

Ac-LEHD-AFC

A4419-5 5 mg
EUR 216
Description: Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

PETCM

A4420-50 50 mg
EUR 383
Description: PETCM is an activator of caspase-3 [1]. Caspase-3 is a member of the cysteine-aspartic acid protease family and interacts with caspase-8 and caspase-9. Sequential activation of caspases plays an important role in cell apoptosis.

L 006235

A4422-10 10 mg
EUR 421
Description: IC50: 0.25 nML-006235 is a potent and selective inhibitor of Cathepsin K.In vitro: After dilution of L-006235 to 0.05 nM, the cathepsin K enzyme activity was initially inhibited.

L 006235

A4422-50 50 mg
EUR 1617
Description: IC50: 0.25 nML-006235 is a potent and selective inhibitor of Cathepsin K.In vitro: After dilution of L-006235 to 0.05 nM, the cathepsin K enzyme activity was initially inhibited.

SID 26681509

A4424-10 10 mg
EUR 399
Description: IC50: 56 nMSID 26681509 is a potent and reversible human cathepsin L inhibitor.The cathepsins have been found to comprise a family of lysosomal protease enzymes whose primary functions, such as protein degradation, play a keyl role in normal cellular homeostasis.

SID 26681509

A4424-50 50 mg
EUR 1520
Description: IC50: 56 nMSID 26681509 is a potent and reversible human cathepsin L inhibitor.The cathepsins have been found to comprise a family of lysosomal protease enzymes whose primary functions, such as protein degradation, play a keyl role in normal cellular homeostasis.

DPPI 1c hydrochloride

A4425-1 1 mg
EUR 226
Description: Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 ?M). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge.

DPPI 1c hydrochloride

A4425-10 10 mg
EUR 431
Description: Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 ?M). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge.

K 579

A4426-10 10 mg
EUR 431
Description: Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC50 values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats.

K 579

A4426-50 50 mg
EUR 1656
Description: Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC50 values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats.

NVP DPP 728 dihydrochloride

A4427-10 10 mg
EUR 273
Description: NVP DPP 728 dihydrochlorideDescription:Ki: Inhibit human DPP-IV amidolytic activity with a Ki of 11 nM [1]Inhibitors of dipeptidyl peptidase 4, also known as DPP-4 inhibitors or gliptins, are a class of oral hypoglycemics that can be used to treat diabetes mellitus type 2.

NVP DPP 728 dihydrochloride

A4427-5.1 10 mM (in 1mL DMSO)
EUR 224
Description: NVP DPP 728 dihydrochlorideDescription:Ki: Inhibit human DPP-IV amidolytic activity with a Ki of 11 nM [1]Inhibitors of dipeptidyl peptidase 4, also known as DPP-4 inhibitors or gliptins, are a class of oral hypoglycemics that can be used to treat diabetes mellitus type 2.

NVP DPP 728 dihydrochloride

A4427-50 50 mg
EUR 999
Description: NVP DPP 728 dihydrochlorideDescription:Ki: Inhibit human DPP-IV amidolytic activity with a Ki of 11 nM [1]Inhibitors of dipeptidyl peptidase 4, also known as DPP-4 inhibitors or gliptins, are a class of oral hypoglycemics that can be used to treat diabetes mellitus type 2.

PK 44 phosphate

A4428-10 10 mg
EUR 545
Description: PK 44 phosphateDescription:IC50: 15.8 nm (DPP-IV)The protein encoded by the DPP4 gene is an antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis.

Vialinin A

A4429-1 1 mg
EUR 113
Description: Vialinin A is a potent inhibitor of ubiquitin-specific peptidases with IC50 values of 1.5, 5.9 and 22.3 ?M for ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB), respectively [1].